ARESTIN® - Preserve Your Teeth

ARESTIN® Contains Minocycline, a Proven, Broad-Spectrum Antibiotic1

ARESTIN delivers therapeutic levels of antibiotic with a microsphere delivery system.

arestin perio scaling root planing handle microspheres

ARESTIN® has a delivery system – minocycline microspheres are administered as a powder to allow for easy placement at the base of the pocket.1

Once inserted in the pocket, contact with gingival crevicular fluid hydrolyzes the bioadhesive microspheres, allowing them to immediately adhere to the surrounding surfaces. This also causes water-filled channels to form inside the microspheres, providing for a sustained release of     minocycline over time.2

ARESTIN® can remain active in the pocket for up to 14 days and does not require removal because it is bioresorbable.1,2

ARESTIN® in Action

Watch ARESTIN® help fight periodontal disease in this animated mechanism of action (MOA) video.

https://vimeo.com/53893719

The Active Ingredient in ARESTIN®, Minocycline, Is a Trusted Antimicrobial1

*Two single-blind, Phase III trials comparing ARESTIN® + SRP to SRP alone and SRP + placebo (n=748). SRP was performed for all groups at baseline. ARESTIN® or vehicle was administered to periodontal pockets ≥5 mm in the adjunctive therapy groups at baseline, 3 months, and 6 months. Efficacy was evaluated over 9 months.
REFERENCES: 1. ARESTIN® (minocycline hydrochloride) Microspheres, 1 mg. Prescribing Information. Horsham, PA: OraPharma, Inc.; 2011. 2. Williams RC. Medical progress: periodontal disease. New Engl J Med. 1990;322(6):373-380.

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